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Free tek link polonia porno filim indir. Doubts were later raised about the painting's authenticity. Inan elderly parishioner made international headlines when she attempted to restore a fresco of Jesus Christ in a Spanish church.

The painting, Elias Garcia Martinez's Ecce Homo, became an international phenomenon as a result of the botched restoration. First posted July 15, If you have inside knowledge of a topic in the news, contact the ABC. ABC teams share the story behind the story and insights German old women the making of digital, TV and radio content. Read about our editorial guiding principles and the enforceable standard our journalists follow. Both Labor and the Coalition laid German old women cards on the table weeks ago, creating plenty of opportunities for new issues to fill the German old women.

And on these surprises, both leaders have been caught unawares. By international reporter Michael Vincent. Cutting deals, flipping witnesses and working his way up the food chain German old women Mueller's prosecution of mob boss John Gotti served as a blueprint for his investigation into the US President, writes Michael Vincent. By Ben Hays for Sunday Extra. With an election now just weeks away, "possibly the world's least helpful dictionary" is here to help you navigate the campaign.

Arthur Koepcke's work was based on a crossword puzzle like this German old women. Ben Watkin; file photo. Related Story: Art installation revived after being mistakenly binned by cleaners.

The sculpture originally depicted Nick Wilde, a character from Disney's Zootopia. The artwork was restored by the museum. External Link: Ecce Homo became a tourist drawcard.

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Cesar Manso. Top Stories Another man dies after Melbourne nightclub crowd sprayed by bullets photos Agriculture German old women stands by water buybacks, amid calls for an inquiry Booze heiress pleads guilty in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a German old women he didn't commit.

Here's how he cleared his name 'I'm going to need a drink': Woman watches 5. To study the current therapies used to German old women women with breast cancer aged 70 and above in Germany, a survey of the clinics of the German Breast Group GBG was done.

Svimmade xxx Watch Porn Videos Nude houswives. The Reading-Work-Piece is one of a series of artworks completed by Koepcke in the mids, according to a post on the National Gallery of Denmark's website written by senior research curator Marianne Torp. Ms Torp said Koepcke's works included picture puzzles, crosswords and perception psychology tests, painted in oil on canvas and featuring cuttings from newspapers and magazines. Late last year, an artwork in an Italian museum resembling the aftermath of a large party was binned after cleaners mistook it for actual rubbish. Doubts were later raised about the painting's authenticity. In , an elderly parishioner made international headlines when she attempted to restore a fresco of Jesus Christ in a Spanish church. The painting, Elias Garcia Martinez's Ecce Homo, became an international phenomenon as a result of the botched restoration. First posted July 15, If you have inside knowledge of a topic in the news, contact the ABC. ABC teams share the story behind the story and insights into the making of digital, TV and radio content. Read about our editorial guiding principles and the enforceable standard our journalists follow. Both Labor and the Coalition laid their cards on the table weeks ago, creating plenty of opportunities for new issues to fill the limelight. And on these surprises, both leaders have been caught unawares. By international reporter Michael Vincent. Cutting deals, flipping witnesses and working his way up the food chain — Mueller's prosecution of mob boss John Gotti served as a blueprint for his investigation into the US President, writes Michael Vincent. By Ben Hays for Sunday Extra. With an election now just weeks away, "possibly the world's least helpful dictionary" is here to help you navigate the campaign. Arthur Koepcke's work was based on a crossword puzzle like this one. Ben Watkin; file photo. Related Story: Art installation revived after being mistakenly binned by cleaners. The sculpture originally depicted Nick Wilde, a character from Disney's Zootopia. The artwork was restored by the museum. External Link: Ecce Homo became a tourist drawcard. Cesar Manso. Conflict of Interest None. Geburtshilfe Frauenheilkd. Barinoff , 1 A. Traut , 1 D. Bauerschlag , 2 J. Bischoff , 3 D. Herr , 4 K. Maass , 2 C. Mundhenke , 7 M. Schmidt , 8 K. Schwedler , 9 M. Thill , 10 J. Steffen , 11 S. Loibl , 11 and G. R, Magdeburg Find articles by J. Correspondence Dr. This article has been cited by other articles in PMC. Abstract Aim: Key words: Abstract Zusammenfassung Ziel: Mammakarzinom, Mammamalignom, Metastasierung. Method An online survey was done of physicians registered in the database of the GBG as principal investigators. Questions Number Percentage Do you work in: A tertiary care centre for oncology 66 Resident physician 3 1. A gynaecologist Open in a separate window. Results In all, physicians Number Percentage Would you be interested in participating in a study on chemotherapy for elderly female patients in a neoadjuvant setting? Not ticked 72 Not ticked 29 Not ticked 65 Discussion The aim of this study was to obtain a representative overview of chemotherapy management concepts in Germany in for female patients aged 70—80 with an ECOG 1 performance status. Footnotes Conflict of Interest None. References 1. Robert Koch-Institut; http: Gennari R, Audisio R A. Breast cancer in elderly women. Optimizing the treatment. Breast Cancer Res Treat. Treatment of breast cancer in older women. Breast cancer in older women: Clin Oncol. Management of breast cancer in elderly individuals: Standard treatment of female patients with breast cancer decreases substantially for women aged 70 years and older: Ann Oncol. Grava-Gubins I, Scott S. Effects of various methodologic strategies: Can Fam Physician. How to obtain excellent response rates when surveying physicians. Fam Pract. Burdens and benefits of adjuvant cyclophosphamide, methotrexate, and fluorouracil and tamoxifen for elderly patients with breast cancer: J Clin Oncol. Capecitabine as adjuvant treatment in elderly patients with early breast cancer — an interim safety analysis of the ICE studies. Docetaxel with cyclophosphamide is associated with an overall survivial benefit compared with doxorubicin and cyclophosphamide: Clinical feasibility of neo adjuvant taxane-based chemotherapy in older patients: Breast Cancer Res. Management of elderly patients with breast cancer: Version 3. Support Center Support Center. External link. Please review our privacy policy..

An online survey was carried out with article source sent to physicians registered as principal investigators in the database of the GBG.

The item questionnaire was used to investigate the systematic therapeutic management of year-old patients in different settings. The indication for chemotherapy was taken as a given.

One third of physicians preferred a taxane-based therapy with the anti-angiogenesis inhibitor bevacizumab German old women first-line therapy for primary metastatic cancer and after anthracycline-based therapy.

The chemotherapy regimen prescribed for women with breast cancer aged 70 and above in Germany appears to be relatively standardised and corresponds to the recommendations given in the S3 Guidelines and by the AGO Breast Committee. Women aged 65 to 69 are in first place, with a total of The group German old women 70—74 comes in second, with Women aged 80—85 had an age-specific disease rate of The number of women aged 65 and above in Germany is German old women to double in the next 20 years NCCN as the generation of baby boomers becomes older in Germany, persons born between and are defined by statisticians as part of the baby-boom German old women.

source

German old women

German old women is important to note that certain factors may also be significant in addition to purely chronological age. The preferred therapeutic management of women with breast cancer aged over 65 corresponds to the concepts formulated for younger patients and complies with the concepts outlined in the S3 Guidelines 8 and the therapy recommendations formulated by AGO 9.

However, as was recently reported by Hancke et al. Another recent study by Sautter-Bihl et al. To investigate the current therapeutic management in Germany of women with breast cancer over 70 years of age, a survey of German old women clinics of the German Breast Group German old women was carried out.

German old women

An online survey was done of physicians registered in the database of the GBG as principal investigators. The German old women were contacted once by e-mail; there was no recall system. The main focus when the case-related item questionnaire was developed was on the clinical German old women of individual questions Table 1.

The questionnaire consisted of 11 multiple-choice questions and one open-ended question where only one answer was permitted.

German old women

The questions related to the therapeutic management selected for a patient aged between 70 and 80 with an ECOG performance status of 1, certain stable pre-existing conditions which were managed with medication and did not constitute a contraindication to specific cytostatic drugs. For the purposes of the study, it was assumed that chemotherapy in different settings source, adjuvant, palliative was indicated; the indication for chemotherapy itself was not German old women issue.

The time for response was set at 4 weeks; analysis was done after the data had been anonymised. No comparison between participants and nonparticipants was done. In all, physicians The German old women of participating physicians German old women given in Table 1. With regard to new patients with metastatic breast cancer, one third of participating physicians respectively reported German old women 30—40 and 10—20 patients per year In the event that adjuvant chemotherapy was prescribed in the same patient, the most commonly chosen combination article source Only 2.

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Which regimen would you be most likely to prescribe in this situation? In the next question the clinical situation was altered such that German old women reflected a situation whereby the patient presented with primary metastatic disease. Once again, it was assumed that chemotherapy was indicated. Which regimen would German old women propose as your first-line option? In the event that metastasis was first found in the same patient after a disease-free interval of 2. In contrast, 2.

Calendar netvideogirls Watch XXX Movies Johnny Cumshot. External Link: Ecce Homo became a tourist drawcard. Cesar Manso. Top Stories Another man dies after Melbourne nightclub crowd sprayed by bullets photos Agriculture Department stands by water buybacks, amid calls for an inquiry Booze heiress pleads guilty in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a murder he didn't commit. Here's how he cleared his name 'I'm going to need a drink': Woman watches 5. Chris Lilley's new Netflix show has a problem and it can't be overcome California couple who tortured their 13 children sentenced to life in prison photos Extra hours for safe injecting room to counteract 'honey pot' effect 'Rubbish bin for the water' on a clean-up mission for the oceans European bikie gang members barred from Australia because they 'presented a risk' IMPORTANT: Why you might think twice before filling in those postal vote applications photos Winter arrives early in WA as cold Antarctic burst delivers April snow for first time since Police officer stabbed with hunting knife at Sydney's Central Station stable after surgery New York City Ballet ordered to reinstate male dancers caught in sexting scandal SPORT Live: Connect with ABC News. Got a news tip? Editorial Policies Read about our editorial guiding principles and the enforceable standard our journalists follow. Shorten and Morrison's Spinal Tap moment Both Labor and the Coalition laid their cards on the table weeks ago, creating plenty of opportunities for new issues to fill the limelight. Mueller's mob boss prosecution tactics By international reporter Michael Vincent Cutting deals, flipping witnesses and working his way up the food chain — Mueller's prosecution of mob boss John Gotti served as a blueprint for his investigation into the US President, writes Michael Vincent. The Wonk's Dictionary By Ben Hays for Sunday Extra With an election now just weeks away, "possibly the world's least helpful dictionary" is here to help you navigate the campaign. Top Stories Another man dies after Melbourne nightclub crowd sprayed by bullets Agriculture Department stands by water buybacks, amid calls for an inquiry Booze heiress pleads guilty in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a murder he didn't commit. Chris Lilley's new Netflix show has a problem and it can't be overcome California couple who tortured their 13 children sentenced to life in prison Extra hours for safe injecting room to counteract 'honey pot' effect. Just In Luke Hodge's in-game interviews illustrates growing issue of too much coverage 'I'm going to need a drink': Giants, Dockers kick off Easter Saturday footy Man 'threatens motorists with nail gun during cross-border police chase'. Why you might think twice before filling in those postal vote applications photos Andrew Mallard, jailed for murder he didn't commit, killed in US hit-run crash California couple who tortured their 13 children sentenced to life in prison photos There's a familiar problem with Chris Lilley's new Netflix show Cop's partner tells trial he wouldn't have shot Justine Damond Ruszczyk 'Rubbish bin for the water' on a clean-up mission for the oceans It wouldn't be surprising if Shorten was starting to get nervous Police officer stabbed with hunting knife at Sydney's Central Station stable after surgery Three charged with murder of Brisbane doctor who was gunned down in garage 'The world has changed': Why shows like Blackadder, Young Ones wouldn't work today. Not very far Craig Bellamy continues to shine ahead of grand final rematch with Trent Robinson The Mueller report is here, but the drama is far from over In all the destruction at the Notre Dame, one photo stood out There's one thing all voters, except One Nation's, seem to agree on. Site Map. Media Video Audio Photos. Subscribe Podcasts Newsletter. Connect Contact Us. No comparison between participants and nonparticipants was done. In all, physicians The characteristics of participating physicians are given in Table 1. With regard to new patients with metastatic breast cancer, one third of participating physicians respectively reported seeing 30—40 and 10—20 patients per year In the event that adjuvant chemotherapy was prescribed in the same patient, the most commonly chosen combination Only 2. Which regimen would you be most likely to prescribe in this situation? In the next question the clinical situation was altered such that it reflected a situation whereby the patient presented with primary metastatic disease. Once again, it was assumed that chemotherapy was indicated. Which regimen would you propose as your first-line option? In the event that metastasis was first found in the same patient after a disease-free interval of 2. In contrast, 2. In both groups the percentage of respondents opting for a combination with bevacizumab was Which regimen would you use as your first-line option? Finally, all participants were asked whether they would be interested in participating in clinical studies of elderly patients. Overall, the proposed study designs were tailored with a view to encouraging compliance and took account of co-morbidities and quality of life. The aim of this study was to obtain a representative overview of chemotherapy management concepts in Germany in for female patients aged 70—80 with an ECOG 1 performance status. Participants in the survey consisted of physicians registered as principal investigators of studies by the GBG; thus it can be assumed that this amounts to a pre-selection of participants as these physicians would have a greater clinical and scientific interest in management strategies for these elderly patients. Surprisingly, fully one quarter of respondents were not hospital-based but had their own practice, making them the second largest group of respondents. Most breast centres in this survey treated between and cases with primary cancer very year. As regards the choice of chemotherapies for women without metastasis the results were as follows: The combination of chemotherapy plus bevacizumab reported in one third of the responses shows that this substance has also found a place in the management of elderly patients. If the patient had had previous treatment with anthracyclines and taxanes, a majority of physicians recommended a monotherapy with capecitabine or vinorelbine. It was clear that a combination therapy played no role as first-line option for the management of women with metastatic breast cancer aged 70 or above. When asked about possible study designs, most physicians reported that they would recommend monotherapy with its reduced side-effects in a neo adjuvant setting, even though the current standard consists of a sequential regimen of three substances. In , Malik et al. Despite all the limitations of this study it was a retrospective, single-centre analysis; the data acquisition period was — the authors questioned the role of therapy carried out in accordance with conventional guidelines in this cohort of patients. Loibl et al. The recommendations for the therapeutic management of elderly patients made by the International Society of Geriatric Oncology SIOG and the European Society of Breast Cancer Specialists EUSOMA emphasise that the decision as to whether chemotherapy is indicated should not be based on age alone; it was recommended that patient examination must also include a standardised geriatric assessment The review article by Sautter-Bihl et al. Nevertheless it is indisputable that therapeutic management of this group of patients must be flexible in view of the co-morbidities generally present in this cohort and indications for therapy must therefore be assessed very carefully. The limited data on toxicity and chemotherapeutic management for this group of patients can only remedied by designing and carrying out further clinical studies; the ICE-II study of the GBG could serve as a good example in this context The current therapeutic recommendations of the AGO Breast Committee suggest that such patients should preferably receive chemotherapy as part of a study LOE: Conflict of Interest None. Geburtshilfe Frauenheilkd. Barinoff , 1 A. Traut , 1 D. Bauerschlag , 2 J. Bischoff , 3 D. Herr , 4 K. Maass , 2 C. Mundhenke , 7 M. Schmidt , 8 K. Schwedler , 9 M. Thill , 10 J. Steffen , 11 S. Loibl , 11 and G. R, Magdeburg Find articles by J. Correspondence Dr. This article has been cited by other articles in PMC. Abstract Aim: Key words: Abstract Zusammenfassung Ziel: Mammakarzinom, Mammamalignom, Metastasierung. Method An online survey was done of physicians registered in the database of the GBG as principal investigators. Questions Number Percentage Do you work in: A tertiary care centre for oncology 66 Resident physician 3 1. A gynaecologist Open in a separate window. Results In all, physicians Number Percentage Would you be interested in participating in a study on chemotherapy for elderly female patients in a neoadjuvant setting?.

In both groups the percentage of respondents opting for a combination with bevacizumab was German old women Which regimen would you use as your first-line option?

Finally, all participants were asked whether they would be interested in participating in clinical studies of elderly patients. Overall, the proposed study designs were tailored with a view to encouraging compliance and took account of co-morbidities and quality of life. The aim of this study was to obtain a representative overview of chemotherapy management concepts in Germany in for female patients aged 70—80 with an ECOG 1 performance status.

Participants in the survey consisted of physicians registered as principal investigators of studies by the GBG; thus German old women can be assumed that German old women amounts to a pre-selection of participants as these physicians would have a greater clinical and scientific interest in management strategies for these elderly German old women. Surprisingly, fully one quarter of respondents were not hospital-based but had their own practice, making them the second largest group of respondents.

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Most breast centres in this survey treated between and cases with primary cancer very year. As regards the choice of chemotherapies for women without metastasis the results were as follows: The combination of chemotherapy plus bevacizumab German old women in one third of the responses shows that this substance has also found a place German old women the management of elderly patients. If the patient had had previous treatment with anthracyclines and taxanes, a majority of physicians recommended a monotherapy with capecitabine or vinorelbine.

It was clear that German old women combination therapy played no role as first-line option for the management of women with metastatic breast cancer aged 70 or above. When asked about possible study designs, most physicians reported that they would recommend monotherapy with its reduced side-effects German old women a neo adjuvant setting, even though the current standard consists of a sequential regimen of three substances. InMalik et al.

91-year-old woman fills out crossword that turns out to be $116k artwork in German museum

Despite all the limitations of this study it was a retrospective, single-centre analysis; the data acquisition period was — the authors questioned the role of therapy carried out in accordance with conventional guidelines in this cohort of patients.

Loibl et al. The recommendations for the therapeutic management of elderly patients made by German old women International Society of Geriatric Oncology SIOG and the European Society of Breast Cancer Specialists EUSOMA emphasise that the decision as to German old women chemotherapy is indicated should not be based on age alone; it was recommended that patient examination must also include a standardised geriatric assessment The review article by Sautter-Bihl et al.

Nevertheless it is German old women that therapeutic management of this group of patients must be flexible in German old women of the co-morbidities generally present in this cohort and indications for therapy must therefore be assessed very carefully. The limited data on toxicity and chemotherapeutic management for this group of patients can only remedied by designing and carrying out further clinical studies; the ICE-II study of the GBG learn more here serve as a good example in this context The current therapeutic recommendations of the AGO Breast Committee suggest that such patients should preferably receive German old women as part of a study LOE: Conflict of Interest None.

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Xxxxxm Small Watch Porn Videos Crackwhore pussy. By Ben Hays for Sunday Extra. With an election now just weeks away, "possibly the world's least helpful dictionary" is here to help you navigate the campaign. Arthur Koepcke's work was based on a crossword puzzle like this one. Ben Watkin; file photo. Related Story: Art installation revived after being mistakenly binned by cleaners. The sculpture originally depicted Nick Wilde, a character from Disney's Zootopia. The artwork was restored by the museum. External Link: Ecce Homo became a tourist drawcard. Cesar Manso. Top Stories Another man dies after Melbourne nightclub crowd sprayed by bullets photos Agriculture Department stands by water buybacks, amid calls for an inquiry Booze heiress pleads guilty in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a murder he didn't commit. Here's how he cleared his name 'I'm going to need a drink': Woman watches 5. Chris Lilley's new Netflix show has a problem and it can't be overcome California couple who tortured their 13 children sentenced to life in prison photos Extra hours for safe injecting room to counteract 'honey pot' effect 'Rubbish bin for the water' on a clean-up mission for the oceans European bikie gang members barred from Australia because they 'presented a risk' IMPORTANT: Why you might think twice before filling in those postal vote applications photos Winter arrives early in WA as cold Antarctic burst delivers April snow for first time since Police officer stabbed with hunting knife at Sydney's Central Station stable after surgery New York City Ballet ordered to reinstate male dancers caught in sexting scandal SPORT Live: Connect with ABC News. Got a news tip? Editorial Policies Read about our editorial guiding principles and the enforceable standard our journalists follow. Shorten and Morrison's Spinal Tap moment Both Labor and the Coalition laid their cards on the table weeks ago, creating plenty of opportunities for new issues to fill the limelight. Mueller's mob boss prosecution tactics By international reporter Michael Vincent Cutting deals, flipping witnesses and working his way up the food chain — Mueller's prosecution of mob boss John Gotti served as a blueprint for his investigation into the US President, writes Michael Vincent. The Wonk's Dictionary By Ben Hays for Sunday Extra With an election now just weeks away, "possibly the world's least helpful dictionary" is here to help you navigate the campaign. Top Stories Another man dies after Melbourne nightclub crowd sprayed by bullets Agriculture Department stands by water buybacks, amid calls for an inquiry Booze heiress pleads guilty in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a murder he didn't commit. Chris Lilley's new Netflix show has a problem and it can't be overcome California couple who tortured their 13 children sentenced to life in prison Extra hours for safe injecting room to counteract 'honey pot' effect. Just In Luke Hodge's in-game interviews illustrates growing issue of too much coverage 'I'm going to need a drink': The indication for chemotherapy was taken as a given. One third of physicians preferred a taxane-based therapy with the anti-angiogenesis inhibitor bevacizumab as first-line therapy for primary metastatic cancer and after anthracycline-based therapy. The chemotherapy regimen prescribed for women with breast cancer aged 70 and above in Germany appears to be relatively standardised and corresponds to the recommendations given in the S3 Guidelines and by the AGO Breast Committee. Women aged 65 to 69 are in first place, with a total of The group aged 70—74 comes in second, with Women aged 80—85 had an age-specific disease rate of The number of women aged 65 and above in Germany is expected to double in the next 20 years NCCN as the generation of baby boomers becomes older in Germany, persons born between and are defined by statisticians as part of the baby-boom generation. It is important to note that certain factors may also be significant in addition to purely chronological age. The preferred therapeutic management of women with breast cancer aged over 65 corresponds to the concepts formulated for younger patients and complies with the concepts outlined in the S3 Guidelines 8 and the therapy recommendations formulated by AGO 9. However, as was recently reported by Hancke et al. Another recent study by Sautter-Bihl et al. To investigate the current therapeutic management in Germany of women with breast cancer over 70 years of age, a survey of the clinics of the German Breast Group GBG was carried out. An online survey was done of physicians registered in the database of the GBG as principal investigators. The physicians were contacted once by e-mail; there was no recall system. The main focus when the case-related item questionnaire was developed was on the clinical relevance of individual questions Table 1. The questionnaire consisted of 11 multiple-choice questions and one open-ended question where only one answer was permitted. The questions related to the therapeutic management selected for a patient aged between 70 and 80 with an ECOG performance status of 1, certain stable pre-existing conditions which were managed with medication and did not constitute a contraindication to specific cytostatic drugs. For the purposes of the study, it was assumed that chemotherapy in different settings neoadjuvant, adjuvant, palliative was indicated; the indication for chemotherapy itself was not an issue. The time for response was set at 4 weeks; analysis was done after the data had been anonymised. No comparison between participants and nonparticipants was done. In all, physicians The characteristics of participating physicians are given in Table 1. With regard to new patients with metastatic breast cancer, one third of participating physicians respectively reported seeing 30—40 and 10—20 patients per year In the event that adjuvant chemotherapy was prescribed in the same patient, the most commonly chosen combination Only 2. Which regimen would you be most likely to prescribe in this situation? In the next question the clinical situation was altered such that it reflected a situation whereby the patient presented with primary metastatic disease. Once again, it was assumed that chemotherapy was indicated. Which regimen would you propose as your first-line option? In the event that metastasis was first found in the same patient after a disease-free interval of 2. In contrast, 2. In both groups the percentage of respondents opting for a combination with bevacizumab was Which regimen would you use as your first-line option? Finally, all participants were asked whether they would be interested in participating in clinical studies of elderly patients. Overall, the proposed study designs were tailored with a view to encouraging compliance and took account of co-morbidities and quality of life. The aim of this study was to obtain a representative overview of chemotherapy management concepts in Germany in for female patients aged 70—80 with an ECOG 1 performance status. Participants in the survey consisted of physicians registered as principal investigators of studies by the GBG; thus it can be assumed that this amounts to a pre-selection of participants as these physicians would have a greater clinical and scientific interest in management strategies for these elderly patients. Surprisingly, fully one quarter of respondents were not hospital-based but had their own practice, making them the second largest group of respondents. Most breast centres in this survey treated between and cases with primary cancer very year. As regards the choice of chemotherapies for women without metastasis the results were as follows: The combination of chemotherapy plus bevacizumab reported in one third of the responses shows that this substance has also found a place in the management of elderly patients. If the patient had had previous treatment with anthracyclines and taxanes, a majority of physicians recommended a monotherapy with capecitabine or vinorelbine. It was clear that a combination therapy played no role as first-line option for the management of women with metastatic breast cancer aged 70 or above. When asked about possible study designs, most physicians reported that they would recommend monotherapy with its reduced side-effects in a neo adjuvant setting, even though the current standard consists of a sequential regimen of three substances. In , Malik et al. Despite all the limitations of this study it was a retrospective, single-centre analysis; the data acquisition period was — the authors questioned the role of therapy carried out in accordance with conventional guidelines in this cohort of patients. Loibl et al. The recommendations for the therapeutic management of elderly patients made by the International Society of Geriatric Oncology SIOG and the European Society of Breast Cancer Specialists EUSOMA emphasise that the decision as to whether chemotherapy is indicated should not be based on age alone; it was recommended that patient examination must also include a standardised geriatric assessment The review article by Sautter-Bihl et al. Nevertheless it is indisputable that therapeutic management of this group of patients must be flexible in view of the co-morbidities generally present in this cohort and indications for therapy must therefore be assessed very carefully. The limited data on toxicity and chemotherapeutic management for this group of patients can only remedied by designing and carrying out further clinical studies; the ICE-II study of the GBG could serve as a good example in this context The current therapeutic recommendations of the AGO Breast Committee suggest that such patients should preferably receive chemotherapy as part of a study LOE: Conflict of Interest None. Geburtshilfe Frauenheilkd. Barinoff , 1 A. Traut , 1 D. Bauerschlag , 2 J. Bischoff , 3 D. Herr , 4 K. Maass , 2 C. Mundhenke , 7 M. Schmidt , 8 K..

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Xxxxbfhd Laver Watch Porn Videos Wwwxxxvd Com. Ms Torp said Koepcke's works included picture puzzles, crosswords and perception psychology tests, painted in oil on canvas and featuring cuttings from newspapers and magazines. Late last year, an artwork in an Italian museum resembling the aftermath of a large party was binned after cleaners mistook it for actual rubbish. Doubts were later raised about the painting's authenticity. In , an elderly parishioner made international headlines when she attempted to restore a fresco of Jesus Christ in a Spanish church. The painting, Elias Garcia Martinez's Ecce Homo, became an international phenomenon as a result of the botched restoration. First posted July 15, If you have inside knowledge of a topic in the news, contact the ABC. ABC teams share the story behind the story and insights into the making of digital, TV and radio content. Read about our editorial guiding principles and the enforceable standard our journalists follow. Both Labor and the Coalition laid their cards on the table weeks ago, creating plenty of opportunities for new issues to fill the limelight. And on these surprises, both leaders have been caught unawares. By international reporter Michael Vincent. Cutting deals, flipping witnesses and working his way up the food chain — Mueller's prosecution of mob boss John Gotti served as a blueprint for his investigation into the US President, writes Michael Vincent. By Ben Hays for Sunday Extra. With an election now just weeks away, "possibly the world's least helpful dictionary" is here to help you navigate the campaign. Arthur Koepcke's work was based on a crossword puzzle like this one. Ben Watkin; file photo. Related Story: Art installation revived after being mistakenly binned by cleaners. The sculpture originally depicted Nick Wilde, a character from Disney's Zootopia. The artwork was restored by the museum. External Link: Ecce Homo became a tourist drawcard. Cesar Manso. Top Stories Another man dies after Melbourne nightclub crowd sprayed by bullets photos Agriculture Department stands by water buybacks, amid calls for an inquiry Booze heiress pleads guilty in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a murder he didn't commit. Which regimen would you use as your first-line option? Finally, all participants were asked whether they would be interested in participating in clinical studies of elderly patients. Overall, the proposed study designs were tailored with a view to encouraging compliance and took account of co-morbidities and quality of life. The aim of this study was to obtain a representative overview of chemotherapy management concepts in Germany in for female patients aged 70—80 with an ECOG 1 performance status. Participants in the survey consisted of physicians registered as principal investigators of studies by the GBG; thus it can be assumed that this amounts to a pre-selection of participants as these physicians would have a greater clinical and scientific interest in management strategies for these elderly patients. Surprisingly, fully one quarter of respondents were not hospital-based but had their own practice, making them the second largest group of respondents. Most breast centres in this survey treated between and cases with primary cancer very year. As regards the choice of chemotherapies for women without metastasis the results were as follows: The combination of chemotherapy plus bevacizumab reported in one third of the responses shows that this substance has also found a place in the management of elderly patients. If the patient had had previous treatment with anthracyclines and taxanes, a majority of physicians recommended a monotherapy with capecitabine or vinorelbine. It was clear that a combination therapy played no role as first-line option for the management of women with metastatic breast cancer aged 70 or above. When asked about possible study designs, most physicians reported that they would recommend monotherapy with its reduced side-effects in a neo adjuvant setting, even though the current standard consists of a sequential regimen of three substances. In , Malik et al. Despite all the limitations of this study it was a retrospective, single-centre analysis; the data acquisition period was — the authors questioned the role of therapy carried out in accordance with conventional guidelines in this cohort of patients. Loibl et al. The recommendations for the therapeutic management of elderly patients made by the International Society of Geriatric Oncology SIOG and the European Society of Breast Cancer Specialists EUSOMA emphasise that the decision as to whether chemotherapy is indicated should not be based on age alone; it was recommended that patient examination must also include a standardised geriatric assessment The review article by Sautter-Bihl et al. Nevertheless it is indisputable that therapeutic management of this group of patients must be flexible in view of the co-morbidities generally present in this cohort and indications for therapy must therefore be assessed very carefully. The limited data on toxicity and chemotherapeutic management for this group of patients can only remedied by designing and carrying out further clinical studies; the ICE-II study of the GBG could serve as a good example in this context The current therapeutic recommendations of the AGO Breast Committee suggest that such patients should preferably receive chemotherapy as part of a study LOE: Conflict of Interest None. Geburtshilfe Frauenheilkd. Barinoff , 1 A. Traut , 1 D. Bauerschlag , 2 J. Bischoff , 3 D. Herr , 4 K. Maass , 2 C. Mundhenke , 7 M. Schmidt , 8 K. Schwedler , 9 M. Thill , 10 J. Steffen , 11 S. Loibl , 11 and G. R, Magdeburg Find articles by J. Correspondence Dr. This article has been cited by other articles in PMC. Abstract Aim: Key words: Abstract Zusammenfassung Ziel: Mammakarzinom, Mammamalignom, Metastasierung. Method An online survey was done of physicians registered in the database of the GBG as principal investigators. Questions Number Percentage Do you work in: A tertiary care centre for oncology 66 Resident physician 3 1. A gynaecologist Open in a separate window. Results In all, physicians Number Percentage Would you be interested in participating in a study on chemotherapy for elderly female patients in a neoadjuvant setting? Not ticked 72 Not ticked 29 Not ticked 65 Discussion The aim of this study was to obtain a representative overview of chemotherapy management concepts in Germany in for female patients aged 70—80 with an ECOG 1 performance status. Footnotes Conflict of Interest None. References 1. Robert Koch-Institut; http: Gennari R, Audisio R A. Breast cancer in elderly women. Optimizing the treatment. Breast Cancer Res Treat. Treatment of breast cancer in older women. Breast cancer in older women:.

Updated July 18, here The woman, who was visiting the museum with a group of seniors, reportedly told police she was following instructions on a sign next to the artwork, which read: The German old women is one of a series of artworks completed by Koepcke in the mids, according to a post on the National Gallery of Denmark's website written by senior research curator Marianne Torp.

Ms Torp said Koepcke's works included picture puzzles, crosswords and perception German old women tests, painted in oil on canvas and featuring cuttings from newspapers and magazines.

Late last year, an artwork in an Italian museum resembling the aftermath of a large party was binned after cleaners mistook it for actual rubbish. Doubts were later raised about the painting's authenticity. Inan elderly parishioner made international headlines when she attempted to restore a fresco of Jesus Christ in a German old women church. The painting, Elias Garcia Martinez's Ecce Homo, became an international phenomenon as a result of the botched restoration.

First posted July 15, If you have inside knowledge of a topic in the news, contact the ABC. ABC teams share the story behind the story and insights into the making of digital, TV and radio content. Read about our editorial guiding principles and the enforceable standard our journalists follow. Both Labor and the Coalition German old women their cards on the table weeks ago, creating plenty of opportunities for new issues to fill the limelight.

And on these surprises, both leaders have been caught unawares. By international reporter Michael Vincent. Cutting deals, flipping witnesses and working his German old women up the food chain — Mueller's prosecution of mob boss John Gotti served as a blueprint for his investigation into the US President, writes Michael Vincent.

Ashiyan Xxx Watch Sex Movies Balerian Porn. Ecce Homo became a tourist drawcard. Cesar Manso. Top Stories Another man dies after Melbourne nightclub crowd sprayed by bullets photos Agriculture Department stands by water buybacks, amid calls for an inquiry Booze heiress pleads guilty in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a murder he didn't commit. Here's how he cleared his name 'I'm going to need a drink': Woman watches 5. Chris Lilley's new Netflix show has a problem and it can't be overcome California couple who tortured their 13 children sentenced to life in prison photos Extra hours for safe injecting room to counteract 'honey pot' effect 'Rubbish bin for the water' on a clean-up mission for the oceans European bikie gang members barred from Australia because they 'presented a risk' IMPORTANT: Why you might think twice before filling in those postal vote applications photos Winter arrives early in WA as cold Antarctic burst delivers April snow for first time since Police officer stabbed with hunting knife at Sydney's Central Station stable after surgery New York City Ballet ordered to reinstate male dancers caught in sexting scandal SPORT Live: Connect with ABC News. Got a news tip? Editorial Policies Read about our editorial guiding principles and the enforceable standard our journalists follow. Shorten and Morrison's Spinal Tap moment Both Labor and the Coalition laid their cards on the table weeks ago, creating plenty of opportunities for new issues to fill the limelight. Mueller's mob boss prosecution tactics By international reporter Michael Vincent Cutting deals, flipping witnesses and working his way up the food chain — Mueller's prosecution of mob boss John Gotti served as a blueprint for his investigation into the US President, writes Michael Vincent. The Wonk's Dictionary By Ben Hays for Sunday Extra With an election now just weeks away, "possibly the world's least helpful dictionary" is here to help you navigate the campaign. Top Stories Another man dies after Melbourne nightclub crowd sprayed by bullets Agriculture Department stands by water buybacks, amid calls for an inquiry Booze heiress pleads guilty in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a murder he didn't commit. Chris Lilley's new Netflix show has a problem and it can't be overcome California couple who tortured their 13 children sentenced to life in prison Extra hours for safe injecting room to counteract 'honey pot' effect. Just In Luke Hodge's in-game interviews illustrates growing issue of too much coverage 'I'm going to need a drink': Giants, Dockers kick off Easter Saturday footy Man 'threatens motorists with nail gun during cross-border police chase'. Why you might think twice before filling in those postal vote applications photos Andrew Mallard, jailed for murder he didn't commit, killed in US hit-run crash California couple who tortured their 13 children sentenced to life in prison photos There's a familiar problem with Chris Lilley's new Netflix show Cop's partner tells trial he wouldn't have shot Justine Damond Ruszczyk 'Rubbish bin for the water' on a clean-up mission for the oceans It wouldn't be surprising if Shorten was starting to get nervous Police officer stabbed with hunting knife at Sydney's Central Station stable after surgery Three charged with murder of Brisbane doctor who was gunned down in garage 'The world has changed': Why shows like Blackadder, Young Ones wouldn't work today. Not very far Craig Bellamy continues to shine ahead of grand final rematch with Trent Robinson The Mueller report is here, but the drama is far from over In all the destruction at the Notre Dame, one photo stood out There's one thing all voters, except One Nation's, seem to agree on. Site Map. Media Video Audio Photos. Subscribe Podcasts Newsletter. Connect Contact Us. Change to mobile view. Barinoff , 1 A. Traut , 1 D. Bauerschlag , 2 J. Bischoff , 3 D. Herr , 4 K. Maass , 2 C. Mundhenke , 7 M. Schmidt , 8 K. Schwedler , 9 M. Thill , 10 J. Steffen , 11 S. Loibl , 11 and G. R, Magdeburg Find articles by J. Correspondence Dr. This article has been cited by other articles in PMC. Abstract Aim: Key words: Abstract Zusammenfassung Ziel: Mammakarzinom, Mammamalignom, Metastasierung. Method An online survey was done of physicians registered in the database of the GBG as principal investigators. Questions Number Percentage Do you work in: A tertiary care centre for oncology 66 Resident physician 3 1. A gynaecologist Open in a separate window. Results In all, physicians Number Percentage Would you be interested in participating in a study on chemotherapy for elderly female patients in a neoadjuvant setting? Not ticked 72 Not ticked 29 Not ticked 65 Discussion The aim of this study was to obtain a representative overview of chemotherapy management concepts in Germany in for female patients aged 70—80 with an ECOG 1 performance status. Footnotes Conflict of Interest None. References 1. Robert Koch-Institut; http: Gennari R, Audisio R A. Breast cancer in elderly women. Optimizing the treatment. Breast Cancer Res Treat. Treatment of breast cancer in older women. Breast cancer in older women: Clin Oncol. Management of breast cancer in elderly individuals: Standard treatment of female patients with breast cancer decreases substantially for women aged 70 years and older: Ann Oncol. Grava-Gubins I, Scott S. Effects of various methodologic strategies: Can Fam Physician. How to obtain excellent response rates when surveying physicians. Fam Pract. Burdens and benefits of adjuvant cyclophosphamide, methotrexate, and fluorouracil and tamoxifen for elderly patients with breast cancer: J Clin Oncol. Capecitabine as adjuvant treatment in elderly patients with early breast cancer — an interim safety analysis of the ICE studies. Docetaxel with cyclophosphamide is associated with an overall survivial benefit compared with doxorubicin and cyclophosphamide: Clinical feasibility of neo adjuvant taxane-based chemotherapy in older patients: Breast Cancer Res. Management of elderly patients with breast cancer: Version 3. Support Center Support Center. External link. Please review our privacy policy. You have completed your medical training as, or are training to be: Would you be interested in participating in a study on chemotherapy for elderly female patients in a neoadjuvant setting?.

By Ben Hays for Sunday Extra. With an election now just weeks away, "possibly the world's least helpful dictionary" is here to help you navigate the campaign. Arthur Koepcke's work was based on a crossword puzzle like this one. Ben Watkin; German old women photo. Related Story: Art installation revived after being mistakenly binned by cleaners. The sculpture originally depicted Nick Wilde, a character from Disney's Zootopia.

The artwork was restored by the museum. External Link: Ecce Homo became a tourist drawcard. Cesar German old women.

German court sentences 88-year-old Holocaust denier to jail

Top Stories Another man dies after Melbourne nightclub crowd sprayed by bullets photos Agriculture Department stands by water buybacks, amid calls for an inquiry Booze heiress pleads https://bus.caca.press/post927-sucej.php in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a murder he didn't commit.

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Got a news tip? Editorial Policies Read here our editorial guiding principles and the enforceable standard our journalists follow.

Shorten and Morrison's Spinal Tap moment Both Labor and the Coalition laid German old women cards on the table weeks ago, creating plenty of opportunities for new issues to fill the limelight. Mueller's mob boss prosecution tactics By international reporter Michael Vincent Cutting deals, flipping witnesses and working his way up the food chain — Mueller's prosecution of mob boss John Gotti served as a blueprint for his investigation into the US President, writes Michael Vincent.

The Wonk's Dictionary By German old women Hays for German old women Extra With an election now just weeks away, "possibly the world's least helpful dictionary" is here to help you navigate the campaign. Top Stories Another man dies German old women Melbourne nightclub crowd sprayed by bullets Agriculture Department stands by water buybacks, amid calls for an inquiry Booze heiress pleads guilty in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a murder he didn't commit.

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Chris Lilley's new Netflix show has a problem and it can't be overcome California couple who tortured their 13 children sentenced to life in prison photos Extra hours for safe injecting room to counteract 'honey pot' effect 'Rubbish bin for the water' on a clean-up mission for the oceans European bikie gang members barred from Australia because they 'presented a risk' IMPORTANT: Why you might think twice before filling in those postal vote applications photos Winter arrives early in WA as cold Antarctic burst delivers April snow for first time since Police officer stabbed with hunting knife at Sydney's Central Station stable after surgery New York City Ballet ordered to reinstate male dancers caught in sexting scandal SPORT Live: Connect with ABC News. Got a news tip? Editorial Policies Read about our editorial guiding principles and the enforceable standard our journalists follow. Shorten and Morrison's Spinal Tap moment Both Labor and the Coalition laid their cards on the table weeks ago, creating plenty of opportunities for new issues to fill the limelight. Mueller's mob boss prosecution tactics By international reporter Michael Vincent Cutting deals, flipping witnesses and working his way up the food chain — Mueller's prosecution of mob boss John Gotti served as a blueprint for his investigation into the US President, writes Michael Vincent. The Wonk's Dictionary By Ben Hays for Sunday Extra With an election now just weeks away, "possibly the world's least helpful dictionary" is here to help you navigate the campaign. Top Stories Another man dies after Melbourne nightclub crowd sprayed by bullets Agriculture Department stands by water buybacks, amid calls for an inquiry Booze heiress pleads guilty in case involving cult-like sex slave harem, NXIVM Andrew Mallard spent 12 years in jail for a murder he didn't commit. Chris Lilley's new Netflix show has a problem and it can't be overcome California couple who tortured their 13 children sentenced to life in prison Extra hours for safe injecting room to counteract 'honey pot' effect. Just In Luke Hodge's in-game interviews illustrates growing issue of too much coverage 'I'm going to need a drink': Giants, Dockers kick off Easter Saturday footy Man 'threatens motorists with nail gun during cross-border police chase'. Why you might think twice before filling in those postal vote applications photos Andrew Mallard, jailed for murder he didn't commit, killed in US hit-run crash California couple who tortured their 13 children sentenced to life in prison photos There's a familiar problem with Chris Lilley's new Netflix show Cop's partner tells trial he wouldn't have shot Justine Damond Ruszczyk 'Rubbish bin for the water' on a clean-up mission for the oceans It wouldn't be surprising if Shorten was starting to get nervous Police officer stabbed with hunting knife at Sydney's Central Station stable after surgery Three charged with murder of Brisbane doctor who was gunned down in garage 'The world has changed': Why shows like Blackadder, Young Ones wouldn't work today. Not very far Craig Bellamy continues to shine ahead of grand final rematch with Trent Robinson The Mueller report is here, but the drama is far from over In all the destruction at the Notre Dame, one photo stood out There's one thing all voters, except One Nation's, seem to agree on. Site Map. Media Video Audio Photos. Another recent study by Sautter-Bihl et al. To investigate the current therapeutic management in Germany of women with breast cancer over 70 years of age, a survey of the clinics of the German Breast Group GBG was carried out. An online survey was done of physicians registered in the database of the GBG as principal investigators. The physicians were contacted once by e-mail; there was no recall system. The main focus when the case-related item questionnaire was developed was on the clinical relevance of individual questions Table 1. The questionnaire consisted of 11 multiple-choice questions and one open-ended question where only one answer was permitted. The questions related to the therapeutic management selected for a patient aged between 70 and 80 with an ECOG performance status of 1, certain stable pre-existing conditions which were managed with medication and did not constitute a contraindication to specific cytostatic drugs. For the purposes of the study, it was assumed that chemotherapy in different settings neoadjuvant, adjuvant, palliative was indicated; the indication for chemotherapy itself was not an issue. The time for response was set at 4 weeks; analysis was done after the data had been anonymised. No comparison between participants and nonparticipants was done. In all, physicians The characteristics of participating physicians are given in Table 1. With regard to new patients with metastatic breast cancer, one third of participating physicians respectively reported seeing 30—40 and 10—20 patients per year In the event that adjuvant chemotherapy was prescribed in the same patient, the most commonly chosen combination Only 2. Which regimen would you be most likely to prescribe in this situation? In the next question the clinical situation was altered such that it reflected a situation whereby the patient presented with primary metastatic disease. Once again, it was assumed that chemotherapy was indicated. Which regimen would you propose as your first-line option? In the event that metastasis was first found in the same patient after a disease-free interval of 2. In contrast, 2. In both groups the percentage of respondents opting for a combination with bevacizumab was Which regimen would you use as your first-line option? Finally, all participants were asked whether they would be interested in participating in clinical studies of elderly patients. Overall, the proposed study designs were tailored with a view to encouraging compliance and took account of co-morbidities and quality of life. The aim of this study was to obtain a representative overview of chemotherapy management concepts in Germany in for female patients aged 70—80 with an ECOG 1 performance status. Participants in the survey consisted of physicians registered as principal investigators of studies by the GBG; thus it can be assumed that this amounts to a pre-selection of participants as these physicians would have a greater clinical and scientific interest in management strategies for these elderly patients. Surprisingly, fully one quarter of respondents were not hospital-based but had their own practice, making them the second largest group of respondents. Most breast centres in this survey treated between and cases with primary cancer very year. As regards the choice of chemotherapies for women without metastasis the results were as follows: The combination of chemotherapy plus bevacizumab reported in one third of the responses shows that this substance has also found a place in the management of elderly patients. If the patient had had previous treatment with anthracyclines and taxanes, a majority of physicians recommended a monotherapy with capecitabine or vinorelbine. It was clear that a combination therapy played no role as first-line option for the management of women with metastatic breast cancer aged 70 or above. When asked about possible study designs, most physicians reported that they would recommend monotherapy with its reduced side-effects in a neo adjuvant setting, even though the current standard consists of a sequential regimen of three substances. In , Malik et al. Despite all the limitations of this study it was a retrospective, single-centre analysis; the data acquisition period was — the authors questioned the role of therapy carried out in accordance with conventional guidelines in this cohort of patients. Loibl et al. The recommendations for the therapeutic management of elderly patients made by the International Society of Geriatric Oncology SIOG and the European Society of Breast Cancer Specialists EUSOMA emphasise that the decision as to whether chemotherapy is indicated should not be based on age alone; it was recommended that patient examination must also include a standardised geriatric assessment The review article by Sautter-Bihl et al. Nevertheless it is indisputable that therapeutic management of this group of patients must be flexible in view of the co-morbidities generally present in this cohort and indications for therapy must therefore be assessed very carefully. The limited data on toxicity and chemotherapeutic management for this group of patients can only remedied by designing and carrying out further clinical studies; the ICE-II study of the GBG could serve as a good example in this context The current therapeutic recommendations of the AGO Breast Committee suggest that such patients should preferably receive chemotherapy as part of a study LOE: Conflict of Interest None. Geburtshilfe Frauenheilkd. Barinoff , 1 A. Traut , 1 D. Bauerschlag , 2 J. Bischoff , 3 D. Herr , 4 K. Maass , 2 C. Mundhenke , 7 M. Schmidt , 8 K. Schwedler , 9 M. Thill , 10 J. Steffen , 11 S. Loibl , 11 and G. R, Magdeburg Find articles by J. Correspondence Dr. This article has been cited by other articles in PMC. Abstract Aim: Key words: Abstract Zusammenfassung Ziel:.

Just In Luke Hodge's in-game interviews illustrates growing issue of too German old women coverage 'I'm going to need a drink': Giants, Dockers kick off Easter Saturday footy Man 'threatens motorists with nail gun during cross-border police chase'.

Why you might think twice before filling in those postal vote applications photos Andrew Mallard, Usa sex movies for murder he didn't German old women, killed in US hit-run crash California couple who tortured their 13 children sentenced to life in prison photos There's a familiar problem with Chris Lilley's new Netflix show Cop's partner tells trial he wouldn't have shot Justine Damond Ruszczyk 'Rubbish bin for the water' on a clean-up mission for the oceans It wouldn't be surprising if Shorten was starting to get nervous Police officer stabbed with hunting knife at Sydney's Central Station stable after surgery Three charged with murder of Brisbane doctor who was gunned down in garage 'The world has changed': Why shows like Blackadder, Young Ones wouldn't work today.

Not very far Craig Bellamy continues to shine ahead of grand final rematch with Trent Robinson The Mueller report is here, but the drama is German old women from over In all the destruction at the Notre Dame, German old women photo stood out There's one thing all voters, except One Nation's, seem to agree on.

Site Map. Media Video Audio Photos. Subscribe Podcasts Newsletter. Connect Contact Us. Change to German old women view. Kelly klass really loves a sloppy creampie.

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